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Scientists say that it will damage the lungs so badly that transplantation is the patient's "only hope".
However, it can cause an inflammatory disease called COVID-19.
And those who died of this disease.
The results show that the coronavirus can destroy the "basic frame" of the lungs, making the organs unable to recover.
Scientists believe that under these extreme conditions, lung transplantation is "the only hope for survival."
To date, eight COVID-19 patients have undergone double lung transplants at Northwestern Hospital in the United States, and Memorial Hospital is part of the hospital-which is said to have the highest execution rate of any health system in the world.
The research team added that after receiving a new lung, patients tend to recover quickly.
Lead author Dr. Ankit Bharat said: "We have provided clear evidence that COVID-19 may cause permanent damage to the lungs in some patients, and for these patients, lung transplantation is the only hope for survival."
However, Dr. Len Horovitz from Lenox Hill Hospital in New York City emphasized that extreme surgery is "reserved for a very small number of patients."
Lung transplants are generally considered safe, but they may have side effects.
Dr. Horowitz said: "The complications of transplantation include infection (and possibly even re-use of COVID-19), bacterial infection and possible rejection of the transplanted lung."
After analyzing severe and dead COVID patients, scientists discovered so-called KRT17 cells in the lung tissue of those with irreversible damage.
The same cells are also found in patients with end-stage pulmonary fibrosis, which is the medical term for lung scarring.
"Like pulmonary fibrosis, we found that COVID-19 caused the recruitment of circulating immune cells called monocytes, which may be recruited to the lungs to kill the virus," said co-author Dr. Scott Budinger.
In fibrotic lung, these cells also promote the formation of fibrotic scar tissue.
"These cells can be easily and safely sampled and can also help mark patients who cannot recover from COVID-19."
The same cells may also be the cause of the structural collapse of the lungs.
Dr. Barat said: "The progenitor cells in the lung (basic cells that can become more specialized) necessary for healing can refill lung wounds by moving along the basic underlying framework of the lung matrix."
"When the framework is destroyed, the progenitor cells have nowhere to go, and large holes are formed in the lungs to cover up the infection. This is also an observation that we have made in these patients' arduous transplant operations.
"Think of it this way; after the earthquake, if the basic structure of the building survives, it can still be renovated. However, if it is leveled, the only option is to replace it."
The better news is that the coronavirus has not recovered among patients in the Northwest region who have undergone lung transplants so far.
Although immunosuppressive drugs are used to reduce the risk of rejection of donor organs, this is still feasible.
Scientists have also discovered that patients can be placed on Extracorporeal Membrane Oxygenation (ECMO) while waiting for transplantation, which is like the heart and lungs for life support.
The most recent Northwestern transplant was performed on Thanksgiving. The patient spent 130 days on ECMO, which is the longest time before transplantation in the world.
This is not the first time experts have labeled how the coronavirus affects the structure of the lungs.
November,
It was found that most of the victims caused "extensive lung damage" due to "serious damage to normal lung structure".
Nine out of ten cells also have abnormally large cells caused by the fusion of several smaller cells, which can lead to dangerous inflammation and blood clots.
In June, the doctor
Thousands of survivors need to be summoned to check for pulmonary fibrosis.
Dr. Sam Hare of the British Society said: "So far, in our six-week scan, 20% to 30% of hospitalized patients seem to show early lung scarring. Signs." Chest imaging.
Professor Mauro Giacca of the University Hospital of Trieste previously told Congress that the lungs of some coronavirus victims were completely unrecognizable.
He added that the deceased had been in the hospital for more than a month and "the structure of his lungs was completely broken."
"In some cases, you can't even tell that it was once a lung."
Coronavirus is one of the seven virus categories that are known to infect humans.
Others include Severe Acute Respiratory Syndrome (Sars) and Middle East Respiratory Syndrome (Mers), which caused 774 and 858 deaths in 2002/3 and 2012, respectively.
It is said that 20% to 60% of Sars and Mers survivors experience health problems similar to pulmonary fibrosis.
Over time, this situation usually eases.
"My concern with COVID-19 is that [people infected with non-Sass or Myers] have infected [more] the population," Dr. Halle said.
Since the epidemic was confirmed,
If Thailand’s cannabis planting promoters’ bets pay off, Thais may soon be addicted to cannabis burgers, washed with cannabis-derived beverages, and then refreshed with shower gel and toothpaste infused with plant compounds. Far from a dream in Bangkok, a wide range of Thai companies started investing in cannabis, seeking to become the forerunner in Asia's emerging multi-billion dollar industry after the legalization of the legal use of cannabis and cannabidiol (CBD) in Bangkok. Created a "high" consumer product earlier this year. Cosmetic manufacturers, beverage companies and rubber products businesses are now investing in the use of the plant to develop domestic cannabis cultivation and products: only for research purposes, imports of cannabis and derivatives are allowed.
Russia and China are racing to fill the COVID-19 vaccine gap in Africa, hoping to consolidate their influence on the continent where many countries in Africa have not yet implemented a single injection. But so far, vaccine donations in Beijing and Moscow are very small, the commercial transaction costs they provide are high, and some African governments are cautious about the lack of data. As wealthy countries increase vaccination efforts, Africa does not have enough resources to order vaccines from Pfizer, AstraZeneca, Moderna and Johnson & Johnson.
US President Biden will meet with the leaders of Australia, India and Japan on Friday, which is the core organization of his efforts to deal with China's growing military and economic power. The White House said that the four-nation virtual meeting will show that Biden attaches great importance to the Indo-Pacific region and focuses on the fight against the coronavirus and the way to cooperate on economic growth and the climate crisis. India and Australia emphasized the importance of regional security cooperation, which was promoted by the previous low-level meetings of these four countries.
The minister in charge of vaccination work, Taro Kono, said on Friday that Japan will use special syringes to extract six doses of coronavirus vaccine from each Pfizer vial to vaccinate medical workers. Most of the syringe inventory in Japan is ordinary, and only five doses can be drawn from the vial at a time. This raises concerns that millions of doses may be wasted.
The former US Secretary of State told the Financial Times in an interview that tax adjustments should be "the last resort" and "have a serious impact on the economy, relations and trade." The EU is expected to present its policy before the end of June. Kerry also told the British "Financial Times" that the United States and Europe have not made a final decision on the proposal of Bruno Le Maire, the French Chancellor of the Exchequer, to establish a common classification standard for green finance.
In Dessau, a small town in Germany where one of the Bauhaus art schools is located, a research institute was established in 1921 to produce vaccines on a large scale and later helped strengthen the German Democratic Republic. About 100 years later, the base is preparing to become a one-stop shop to produce COVID-19 vaccines for the pandemic response in Germany. This is just one example of the massive efforts of governments around the world to obtain fragmented vaccine production, which previously caused setbacks that caused EU member states to lose the ability to produce medicines on their own land this year.
Sanofi and Translate Bio said on Friday that they have begun human trials of their mRNA candidate COVID-19 vaccine. This is the second vaccine project of a French drugmaker. The vaccine was based on protein caused by delays last year. Injection. It is the latest vaccine candidate based on a new technology called messenger RNA. After clinical trials showed high efficacy, Pfizer/BioNTech and Moderna initiated the injection.
Australia's embattled defense minister apologized last Friday and withdrew remarks that the former staff officer resolved the latter’s defamation allegations, who said she was raped in the ministerial office in 2019. Domestic media said that after Linda Reynolds was putting pressure on her to deal with the rape allegations, she once referred to Brittany Higgins as a "crouching cow." Prime Minister Scott Morrison clarified that the speech in Reynolds' private office frustrated her because it was suggested that she did not give enough support to Higgins' allegations of rape of colleagues in the Capitol. Suggestions.
The Super 300 US Open of the BWF World Tour is scheduled to be held from July 6 to 11, while the Canadian Open of the Super 100 is scheduled to be held from June 29 to July 4. "The ongoing COVID-19 restrictions and complexity leave local organizers no choice but to cancel the game."
Despite the insistence of many health authorities in the world that it is safe, Thailand and several European countries suspended treatment of the AstraZeneca vaccine on Friday.
Will a little raccoon have a stroke while drinking a latte? Or is there a snake hovering around you after a cup of cappuccino?
March 12-Debjani Ghosh, Chairman of the Software and Service Companies Association, India's National Information and Technology Services Industry Trade Organization, discusses how the coronavirus pandemic affects its members. In the "India Focus" section of "Bloomberg Markets: Asia", she spoke with Rishaad Salamat and Juliette Saly.
As Britain advised its citizens to flee Myanmar on Friday, UN experts warned that the military government may commit “crimes against humanity” while trying to govern.
After a year of failed attempts, China's next-generation Long March 7A was launched from the Wenchang launch site in Hainan Province on Friday. This launch will send the technology verification satellite "Shiyan 9" developed by the China Academy of Aerospace Technology into a geosynchronous orbit that matches the rotation of the earth. 40 minutes later, China Aerospace Science and Technology Corporation (CASC), China's major space contractor, confirmed the success of the launch and obtained the latest insights and analysis on major Chinese news from the "Global Impact" newsletter. The launch was carried out after the failed launch in March 2020. Pressure loss occurs after the first stage is separated, causing engine failure. That was the first launch of CZ-7A (Long March 7A). CASC plans to launch CZ-7A three to five times a year before 2025. Friday’s successful launch is a breakthrough for China, as the Long March 7A can increase the payload weight of the geosynchronous orbit from 5.5 tons to 7 tons, according to the CASC official release on WeChat. CZ-7A is a three-stage medium-rise liquid fuel rocket. It is expected to play an important role in China's high-orbit missions. The rocket is 60 meters (197 feet) long and weighs 573 tons (632 short tons). It is mainly used for the launch of geostationary satellites. It can be launched from Wenchang Station and Xichang Satellite Launch Center in Sichuan Province. China and Russia announced plans for a joint lunar space station. According to Chinese media reports, China plans to build its space station through 11 launches from 2021 to 2022. These launches include three module launches, four Tianzhou cargo missions and four manned flights. It plans to launch the core module of the Tiangong space station this spring, and plans to complete the construction before the end of next year. An article on the news portal 163.com stated that CZ-7A is a variant of CZ-7, and its main design purpose is to launch a cargo spacecraft to a Chinese space station. With a payload capacity of more than 13.5 tons, CZ-7 can send more supplies to space at a time, thereby helping future Chinese astronauts stay longer on the space station. The rocket research team stated in 2017 that the "Long March March 7th" achieved 12 breakthroughs and mastered 96 key technologies, representing the latest capabilities of China's rocket research and development. I was busy with China's space program last year. The Beidou satellite chain is completed, and the Tiantian-1 Mars probe is launched into space. The year ended with the success of the E-5 moon landing mission, which collected rock samples from the surface of the moon and sent them back to Earth. China also conducted a secret flight test, which is believed to be a fixed-wing reusable space shuttle similar to the US space shuttle. China, which can carry 20 satellites, will enter the heavy rocket competition with a planned 100-ton carrier rocket. Xi Jinping urges China to approach the launch of the first space station module. The exploration era China has completed the last link of the high-resolution earth observation satellite chain. The successful launch of the long satellite on March 7A, which was restored after the failed rocket launch in 2009, appeared for the first time in the South China Morning Post. For the latest news from the South China Morning Post, please download our mobile app. Copyright 2021.
Democrats and progressive policy advocates praised President Joe Biden's $1.9 trillion COVID-19 relief plan, which serves as a social safety net for generations to come, providing food and housing assistance, and more medical services As well as direct assistance to families, this amounts to a broad-based attack on the poverty cycle. The package includes more than $6 billion for food safety-related programs, more than $25 billion in emergency rental assistance, nearly $10 billion in emergency mortgage assistance for homeowners, and an expanded unemployment payment period extended to early September . Help families and individuals survive and recover from the economic difficulties caused by the pandemic. Ellen Vollinger, legal director of the Food Research and Action Center, a food security advocacy organization, said: "When you stand up and take a look, you can really appreciate its vast scope."
The New Zealand defender and Italian challenger Luna Rossa each won a match on the second day of the game in Auckland on Friday, and tied for 2-2 in the 13 best match series. The America’s Cup games of the past 170 years are usually not over, but as long as the wind stays smooth and starts to exert a huge influence, this game seems likely to continue. Luna Rossa won the start of the game in the first game on Friday and entered the game in 37 seconds. The New Zealand team started in the second game and won in 63 seconds.
Dante’s "Divine Comedy", considered one of the greatest literary works in the world, was exposed after the displacement that Italian judicial experts now want to correct. Seven centuries have passed.
Artists such as Hwang Hyunjin and Ji Soo apologized for their past actions, while other artists such as Jo Byung Gyu and Yoo Kihyun denied the accusations against them and threatened legal action.
March 12-After the Biden government imposed new restrictions on some of the suppliers of Huawei Technologies Co., Ltd., one of the biggest issues between China and the United States once again became the focus of attention. Chen Shiyin of Bloomberg reports "Bloomberg Markets: China Open."
